Publications

2012

Sutphin, G. L., E. Bishop, M. E. Yanos, R. M. Moller, and M. Kaeberlein, "Caffeine extends life span, improves healthspan, and delays age-associated pathology in Caenorhabditis elegans.", Longev Healthspan, vol. 1, pp. 9, 2012. PMCID: PMC3922918  PMID: 24764514

2011

Louderbough, J. M. V., and J. A. Schroeder, "Understanding the dual nature of CD44 in breast cancer progression.", Mol Cancer Res, vol. 9, issue 12, pp. 1573-86, 2011 Dec. PMID: 21970856
Yao, G., C. Tan, M. West, J. R. Nevins, and L. You, "Origin of bistability underlying mammalian cell cycle entry.", Mol Syst Biol, vol. 7, pp. 485, 2011 Apr 26. PMCID: PMC3101952  PMID: 21525871
Xu, X., X. Liu, S. Ge, J. D. Jensen, F. Hu, X. Li, Y. Dong, R. N. Gutenkunst, L. Fang, L. Huang, et al., "Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes.", Nat Biotechnol, vol. 30, issue 1, pp. 105-11, 2011 Dec 11. PMID: 22158310
Gutenkunst, R. N., D. Coombs, T. Starr, M. L. Dustin, and B. Goldstein, "A biophysical model of cell adhesion mediated by immunoadhesin drugs and antibodies.", PLoS One, vol. 6, issue 5, pp. e19701, 2011. PMCID: PMC3100730  PMID: 21629715
Zheng, X., L. Siu- Lun Cheung, J. A. Schroeder, L. Jiang, and Y. Zohar, "Cell receptor and surface ligand density effects on dynamic states of adhering circulating tumor cells.", Lab Chip, vol. 11, issue 20, pp. 3431-9, 2011 Oct 21. PMCID: PMC6765388  PMID: 21853194
Wong, J. V., G. Yao, J. R. Nevins, and L. You, "Viral-mediated noisy gene expression reveals biphasic E2f1 response to MYC.", Mol Cell, vol. 41, issue 3, pp. 275-85, 2011 Feb 04. PMCID: PMC3044932  PMID: 21292160
Kruegel, U., B. Robison, T. Dange, G. Kahlert, J. R. Delaney, S. Kotireddy, M. Tsuchiya, S. Tsuchiyama, C. J. Murakami, J. Schleit, et al., "Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae.", PLoS Genet, vol. 7, issue 9, pp. e1002253, 2011 Sep. PMCID: PMC3169524  PMID: 21931558
Chylek, L. A., B. Hu, M. L. Blinov, T. Emonet, J. R. Faeder, B. Goldstein, R. N. Gutenkunst, J. M. Haugh, T. Lipniacki, R. G. Posner, et al., "Guidelines for visualizing and annotating rule-based models.", Mol Biosyst, vol. 7, issue 10, pp. 2779-95, 2011 Oct. PMCID: PMC3168731  PMID: 21647530
Aldy, K. N., N. C. Horton, P. A. Mathew, and S. O. Mathew, "2B4+ CD8+ T cells play an inhibitory role against constrained HIV epitopes.", Biochem Biophys Res Commun, vol. 405, issue 3, pp. 503-7, 2011 Feb 18. PMCID: PMC3063451  PMID: 21256826
Buchan, J.R., J-H. Yoon, and R. Parker, "Stress-specific composition, assembly and kinetics of stress granules in Saccharomyces cerevisiae.", J Cell Sci, vol. 124, issue Pt 2, pp. 228-39, 2011 Jan 15. PMCID: PMC3010191  PMID: 21172806
Locke, D. P., LD. W. Hillier, W. C. Warren, K. C. Worley, L. V. Nazareth, D. M. Muzny, S-P. Yang, Z. Wang, A. T. Chinwalla, P. Minx, et al., "Comparative and demographic analysis of orang-utan genomes.", Nature, vol. 469, issue 7331, pp. 529-33, 2011 Jan 27. PMCID: PMC3060778  PMID: 21270892
Zheng, X., L. Siu- Lun Cheung, J. A. Schroeder, L. Jiang, and Y. Zohar, "A high-performance microsystem for isolating circulating tumor cells.", Lab Chip, vol. 11, issue 19, pp. 3269-76, 2011 Oct 07. PMCID: PMC6765387  PMID: 21837324
Wong, J. V., G. Yao, J. R. Nevins, and L. You, "Using noisy gene expression mediated by engineered adenovirus to probe signaling dynamics in mammalian cells.", Methods Enzymol, vol. 497, pp. 221-37, 2011. PMID: 21601089
Burnett, C., S. Valentini, F. Cabreiro, M. Goss, M. Somogyvári, M. D. Piper, M. Hoddinott, G. L. Sutphin, V. Leko, J. J. McElwee, et al., "Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.", Nature, vol. 477, issue 7365, pp. 482-5, 2011 Sep 21. PMCID: PMC3188402  PMID: 21938067
Little, E. J., P. W. Dunten, J. Bitinaite, and N. C. Horton, "New clues in the allosteric activation of DNA cleavage by SgrAI: structures of SgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA.", Acta Crystallogr D Biol Crystallogr, vol. 67, issue Pt 1, pp. 67-74, 2011 Jan. PMCID: PMC3016018  PMID: 21206063
Skar, H., R. N. Gutenkunst, K. Wilbe Ramsay, A. Alaeus, J. Albert, and T. Leitner, "Daily sampling of an HIV-1 patient with slowly progressing disease displays persistence of multiple env subpopulations consistent with neutrality.", PLoS One, vol. 6, issue 8, pp. e21747, 2011. PMCID: PMC3149046  PMID: 21829600
Bolger, T. A., and S. R. Wente, "Gle1 is a multifunctional DEAD-box protein regulator that modulates Ded1 in translation initiation.", J Biol Chem, vol. 286, issue 46, pp. 39750-9, 2011 Nov 18. PMCID: PMC3220593  PMID: 21949122
Louderbough, J. M. V., J. A. Brown, R. B. Nagle, and J. A. Schroeder, "CD44 Promotes Epithelial Mammary Gland Development and Exhibits Altered Localization during Cancer Progression.", Genes Cancer, vol. 2, issue 8, pp. 771-81, 2011 Aug. PMCID: PMC3278897  PMID: 22393462
Delaney, J. R., G. L. Sutphin, B. Dulken, S. Sim, J. R. Kim, B. Robison, J. Schleit, C. J. Murakami, D. Carr, E. H. An, et al., "Sir2 deletion prevents lifespan extension in 32 long-lived mutants.", Aging Cell, vol. 10, issue 6, pp. 1089-91, 2011 Dec. PMCID: PMC3215821  PMID: 21902802
Gravel, S., B. M. Henn, R. N. Gutenkunst, A. R. Indap, G. T. Marth, A. G. Clark, F. Yu, R. A. Gibbs, and C. D. Bustamante, "Demographic history and rare allele sharing among human populations.", Proc Natl Acad Sci U S A, vol. 108, issue 29, pp. 11983-8, 2011 Jul 19. PMCID: PMC3142009  PMID: 21730125

2010

Alcázar-Román, A. R., T. A. Bolger, and S. R. Wente, "Control of mRNA export and translation termination by inositol hexakisphosphate requires specific interaction with Gle1.", J Biol Chem, vol. 285, issue 22, pp. 16683-92, 2010 May 28. PMCID: PMC2878036  PMID: 20371601
Park, C. K., A. P. Stiteler, S. Shah, I. M Ghare, J. Bitinaite, and N. C. Horton, "Activation of DNA cleavage by oligomerization of DNA-bound SgrAI.", Biochemistry, vol. 49, issue 41, pp. 8818-30, 2010 Oct 19. PMCID: PMC2972665  PMID: 20836535
Louderbough, J. M. V., J. I. Lopez, and J. A. Schroeder, "Matrix hyaluronan alters epidermal growth factor receptor-dependent cell morphology.", Cell Adh Migr, vol. 4, issue 1, pp. 26-31, 2010 Jan-Mar. PMCID: PMC2852554  PMID: 20009574
Colvin, J., M. I. Monine, R. N. Gutenkunst, W. S. Hlavacek, D. D. Von Hoff, and R. G. Posner, "RuleMonkey: software for stochastic simulation of rule-based models.", BMC Bioinformatics, vol. 11, pp. 404, 2010 Jul 30. PMCID: PMC2921409  PMID: 20673321

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