Publications
2011
Little, E. J., P. W. Dunten, J. Bitinaite, and N. C. Horton, "New clues in the allosteric activation of DNA cleavage by SgrAI: structures of SgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA.", Acta Crystallogr D Biol Crystallogr, vol. 67, issue Pt 1, pp. 67-74, 2011 Jan.
PMCID: PMC3016018 PMID: 21206063
Aldy, K. N., N. C. Horton, P. A. Mathew, and S. O. Mathew, "2B4+ CD8+ T cells play an inhibitory role against constrained HIV epitopes.", Biochem Biophys Res Commun, vol. 405, issue 3, pp. 503-7, 2011 Feb 18.
PMCID: PMC3063451 PMID: 21256826
Wong, J. V., G. Yao, J. R. Nevins, and L. You, "Using noisy gene expression mediated by engineered adenovirus to probe signaling dynamics in mammalian cells.", Methods Enzymol, vol. 497, pp. 221-37, 2011.
PMID: 21601089
Burnett, C., S. Valentini, F. Cabreiro, M. Goss, M. Somogyvári, M. D. Piper, M. Hoddinott, G. L. Sutphin, V. Leko, J. J. McElwee, et al., "Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.", Nature, vol. 477, issue 7365, pp. 482-5, 2011 Sep 21.
PMCID: PMC3188402 PMID: 21938067
Bolger, T. A., and S. R. Wente, "Gle1 is a multifunctional DEAD-box protein regulator that modulates Ded1 in translation initiation.", J Biol Chem, vol. 286, issue 46, pp. 39750-9, 2011 Nov 18.
PMCID: PMC3220593 PMID: 21949122
2010
Park, C. K., H. K. Joshi, A. Agrawal, I. M Ghare, E. J. Little, P. W. Dunten, J. Bitinaite, and N. C. Horton, "Domain swapping in allosteric modulation of DNA specificity.", PLoS Biol, vol. 8, issue 12, pp. e1000554, 2010 Dec 07.
PMCID: PMC2998434 PMID: 21151881
Bitler, B. G., and J. A. Schroeder, "Anti-cancer therapies that utilize cell penetrating peptides.", Recent Pat Anticancer Drug Discov, vol. 5, issue 2, pp. 99-108, 2010 Jun.
PMCID: PMC7485746 PMID: 19961434
Lee, T. J., G. Yao, D. C. Bennett, J. R. Nevins, and L. You, "Stochastic E2F activation and reconciliation of phenomenological cell-cycle models.", PLoS Biol, vol. 8, issue 9, 2010 Sep 21.
PMCID: PMC2943438 PMID: 20877711
Alcázar-Román, A. R., T. A. Bolger, and S. R. Wente, "Control of mRNA export and translation termination by inositol hexakisphosphate requires specific interaction with Gle1.", J Biol Chem, vol. 285, issue 22, pp. 16683-92, 2010 May 28.
PMCID: PMC2878036 PMID: 20371601
Bitler, B. G., A. Goverdhan, and J. A. Schroeder, "MUC1 regulates nuclear localization and function of the epidermal growth factor receptor.", J Cell Sci, vol. 123, issue Pt 10, pp. 1716-23, 2010 May 15.
PMCID: PMC2864713 PMID: 20406885
Buchan, J.R., T. Nissan, and R. Parker, "Analyzing P-bodies and stress granules in Saccharomyces cerevisiae.", Methods Enzymol, vol. 470, pp. 619-40, 2010.
PMID: 20946828
Abecasis, G. R., D. Altshuler, A. Auton, L. D. Brooks, R. M. Durbin, R. A. Gibbs, M. E. Hurles, and G. A. McVean, "A map of human genome variation from population-scale sequencing.", Nature, vol. 467, issue 7319, pp. 1061-73, 2010 Oct 28.
PMCID: PMC3042601 PMID: 20981092
Horton, N. C., and C. K. Park, "Crystallization of zinc finger proteins bound to DNA.", Methods Mol Biol, vol. 649, pp. 457-77, 2010.
PMID: 20680852
Park, C. K., A. P. Stiteler, S. Shah, I. M Ghare, J. Bitinaite, and N. C. Horton, "Activation of DNA cleavage by oligomerization of DNA-bound SgrAI.", Biochemistry, vol. 49, issue 41, pp. 8818-30, 2010 Oct 19.
PMCID: PMC2972665 PMID: 20836535
Louderbough, J. M. V., J. I. Lopez, and J. A. Schroeder, "Matrix hyaluronan alters epidermal growth factor receptor-dependent cell morphology.", Cell Adh Migr, vol. 4, issue 1, pp. 26-31, 2010 Jan-Mar.
PMCID: PMC2852554 PMID: 20009574
Colvin, J., M. I. Monine, R. N. Gutenkunst, W. S. Hlavacek, D. D. Von Hoff, and R. G. Posner, "RuleMonkey: software for stochastic simulation of rule-based models.", BMC Bioinformatics, vol. 11, pp. 404, 2010 Jul 30.
PMCID: PMC2921409 PMID: 20673321
Flowers, M., J. A. Schroeder, A. D. Borowsky, D. G. Besselsen, C. A. Thomson, R. Pandey, and P. A. Thompson, "Pilot study on the effects of dietary conjugated linoleic acid on tumorigenesis and gene expression in PyMT transgenic mice.", Carcinogenesis, vol. 31, issue 9, pp. 1642-9, 2010 Sep.
PMCID: PMC2930807 PMID: 20624750
2009
Cheung, L. Siu Lun, X. Zheng, A. Stopa, J. C. Baygents, R. Guzman, J. A. Schroeder, R. L. Heimark, and Y. Zohar, "Detachment of captured cancer cells under flow acceleration in a bio-functionalized microchannel.", Lab Chip, vol. 9, issue 12, pp. 1721-31, 2009 Jun 21.
PMID: 19495456
Andrés, A. M., M. J. Hubisz, A. Indap, D. G. Torgerson, J. D. Degenhardt, A. R. Boyko, R. N. Gutenkunst, T. J. White, E. D. Green, C. D. Bustamante, et al., "Targets of balancing selection in the human genome.", Mol Biol Evol, vol. 26, issue 12, pp. 2755-64, 2009 Dec.
PMCID: PMC2782326 PMID: 19713326
Mehta, R., K. A. Steinkraus, G. L. Sutphin, F. J. Ramos, L. S. Shamieh, A. Huh, C. Davis, D. Chandler-Brown, and M. Kaeberlein, "Proteasomal regulation of the hypoxic response modulates aging in C. elegans.", Science, vol. 324, issue 5931, pp. 1196-8, 2009 May 29.
PMCID: PMC2737476 PMID: 19372390
Bitler, B. G., I. Menzl, C. L. Huerta, B. Sands, W. Knowlton, A. Chang, and J. A. Schroeder, "Intracellular MUC1 peptides inhibit cancer progression.", Clin Cancer Res, vol. 15, issue 1, pp. 100-9, 2009 Jan 01.
PMCID: PMC2676873 PMID: 19118037
Gutenkunst, R. N., R. D. Hernandez, S. H. Williamson, and C. D. Bustamante, "Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data.", PLoS Genet, vol. 5, issue 10, pp. e1000695, 2009 Oct.
PMCID: PMC2760211 PMID: 19851460
Mori, S., J. T. Chang, E. R. Andrechek, N. Matsumura, T. Baba, G. Yao, J. W. Kim, M. Gatza, S. Murphy, and J. R. Nevins, "Anchorage-independent cell growth signature identifies tumors with metastatic potential.", Oncogene, vol. 28, issue 31, pp. 2796-805, 2009 Aug 06.
PMCID: PMC3008357 PMID: 19483725
Nielsen, R., M. J. Hubisz, I. Hellmann, D. Torgerson, A. M. Andrés, A. Albrechtsen, R. Gutenkunst, M. D. Adams, M. Cargill, A. Boyko, et al., "Darwinian and demographic forces affecting human protein coding genes.", Genome Res, vol. 19, issue 5, pp. 838-49, 2009 May.
PMCID: PMC2675972 PMID: 19279335
Buchan, J.R., and R. Parker, "Eukaryotic stress granules: the ins and outs of translation.", Mol Cell, vol. 36, issue 6, pp. 932-41, 2009 Dec 25.
PMCID: PMC2813218 PMID: 20064460