Brian Soong

MCB PhD Student
Department: 
MCB

MCB Program Start: 

2020

Undergrad School: 

Azusa Pacific University

Undergrad Degree: 

B.S. Biochemistry

Undergrad Graduation Year: 

2019

Research Advisor and Department: 

Thomas Tomasiak, Chemistry and Biochemistry

Research Topic: 

My research focuses on understanding the substrate binding and transport mechanism in the human L-cystine/L-glutamate antiporter, xCT. xCT plays an essential role in regulating cellular redox homeostasis and is upregulated in cancer to combat oxidative stress build-up. Therefore, my project goal is to elucidate the functional mechanism of xCT using biochemical and structural techniques so that we may design chemotherapeutics for cancer treatments.

Honors and Awards:

T-32 Ruth L. Kirschstein Institutional National Research Service Award (2021)
University of Arizona Galileo Circle Scholarship (2021)
T-32 Ruth L. Kirschstein Institutional National Research Service Award (2020)
Tri-Beta Biological Honor Society John C. Johnson Award (2018)
Gencarella scholar (2018)
Tri-Beta Biological Honor Society Research Grant (2017)

Hobbies and Interests: 

I am a fairly outdoors person, so I enjoy doing things like hiking and kayaking a lot. I also play sand volleyball every week.

Guiding Principle:

Do what excites.

Publications

2020

Anderson, S. D., A. Tabassum, J. Kyung Yeon, G. Sharma, P. Santos, T. Hang Soong, Y. Win Thu, I. Nies, T. Kurita, A. Chandler, et al., "In silico prediction of ARB resistance: A first step in creating personalized ARB therapy.", PLoS Comput Biol, vol. 16, issue 11, pp. e1007719, 2020 11. PMCID: PMC7725353 PMID: 33237899