Seminar Title: "RNP Granules in Health and Disease"
When
Sept. 29, 2026, 3:30 – 4:45 p.m.
Where
ENR2, Room S107
Presenter Details
Roy Parker, Distinguished Professor, Biochemistry, Univ of Colorado
Seminar Information
Eukaryotic cells contain large membrane-less assemblies of proteins and RNAs, referred to as RNP granules. RNP granules assemble through a combination of protein and RNA driven condensation with intermolecular RNA-RNA interactions stabilizing RNP granules once formed. This process is promoted by proteins, referred to as RNA condensors, that enhance intermolecular RNA-RNA interactions, and limited by a system of "RNA decondensors" that destabilize intermolecular RNA interactions to allow for proper RNP dynamics. RNP granules can also play roles in viral infections and neurodegenerative diseases including affecting the development and mechanisms of tau aggregation in tauopathies.
Seminar Host
BMCB Grad Students and Ross Buchan
Contacts
Whitney DeGroot