Zarnescu lab helps explain the ALS mechanisms

ALS (Lou Gehrig's Disease) is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Daniela Zarnescu, associate professor at Molecular and Cellular Biology, and Alyssa Coyne, a graduate student in the UA's Neuroscience Graduate Interdisciplinary Program, together with their colleagues, have identified a a clear molecular defect at the junctions between neurons and muscles, which may provide greater insight into the fundamental mechanisms of ALS. Their finding was published in the Journal of Neuroscience.