When
Where
Harvill, Room 204
Presenter Details
Lukasz Bugaj
Seminar Information
The Bugaj Lab engineers precision tools to manipulate living cells, with a focus on protein condensation, cell signaling, and cancer biology. I will highlight our recent work on new protein switches that respond to changes in light or temperature, which collectively allow dynamic, non-invasive control of cells in culture and deep within animal tissues. I will then describe how these and other tools help us understand protein condensation and signaling in cancer, with a focus on receptor tyrosine kinase fusion oncoproteins. I will detail our findings on the role of condensation in oncogenic signaling and in the development of drug resistance.
Seminar Host
Andrew Paek, MCB, UArizona