Tissiana Menna Vallecillo

AMP Student

Anticipated AMP Graduation Date:   May 2022

Bachelor's Degree: BS, Molecular and Cellular Biology, University of Arizona

Research PI: Dr. Joyce Schroeder Molecular and Cellular Biology

Research Topic:   Compared to other subtypes, the triple-negative subtype of breast cancer (TNBC) is associated with the poorest prognosis. I am working with Dr. Joyce Schroeder to understand the mechanisms driving this poor prognosis- notably the regulation of inflammation downstream of epidermal growth factor receptor (EGFR) stimulation during TNBC progression. Our work will help reveal new therapeutic targets and may help explain the ineffectiveness of canonical EGFR-targeting therapies in treating TNBC. 

Honors and Awards 

I am a 2018 Flinn Scholar, and 2020 Galileo Circle Scholar

Publications

2021

Blawn, K. T., K. L. Kellohen, E. A. Galloway, J. Wahl, A. Vivek, V. G. Verkhovsky, N. K. Barker, K. E. Cottier, T. G. Vallecillo, P. R. Langlais, et al., "Sex hormones regulate NHE1 functional expression and brain endothelial proteome to control paracellular integrity of the blood endothelial barrier.", Brain Res, vol. 1763, pp. 147448, 2021 Jul 15. PMID: 33771519