Johri, P., Eyre-Walker, A., Gutenkunst, R. N., Lohmueller, K. E., & Jensen, J. D.
Genome Biology and Evolution.
The distribution of mutations among individuals within a population is shaped natural selection and by the history of that population (bottlenecks, migration with other populations, etc.). Current methods for analyzing DNA sequences typically focus on learning about selection or history, but not both. This is problematic because selection and history can create similar pattern of mutations. In this review article, authors discuss the potential for simultaneously learning about selection and history, which would be a major advance for the field of population genetics.
Link to paper: https://doi.org/10.1093/gbe/evac088
Publish Date:
Sep 29, 2022